Angiogenesis: The Origin of Skin Redness from the Use of Retinoids

Certainly! Here’s the translation into American English:

The dermocosmetic directors of well-known brands such as Perricone MD, Medik8, and Byoode have highlighted the significant evolution of retinoids, emphasizing that their proper use can be indicative of good skin health. These products, which include retinol and retinal, are known to cause reactions like redness and itching after application. However, new formulations have been designed to minimize these adverse effects.

Estefanía Nieto from Medik8 mentions that it’s common to experience mild inflammation at the beginning of treatment, which does not necessarily require stopping use. Meanwhile, Mireia Fernández from Perricone MD holds that with proper application and an adjustment period, the skin can become accustomed to retinoids, allowing for daily use without discomfort in about a month.

It’s essential to differentiate between irritation caused by retinoids and a phenomenon known as angiogenesis, which, according to Raquel González from Byoode, is an indicator that the treatment is effective. After a month of use, redness may be attributed to the dilation of blood vessels, which improves circulation and promotes skin regeneration.

The key to recognizing these differences lies in the speed and nature of the reactions. Irritation occurs immediately and calls for attention, whereas angiogenesis is a more gradual process that manifests as the skin adapts to the retinoid. The latter symptom is considered positive, as it indicates an improvement in skin health and collagen production.

Experts have pointed out that if redness persists beyond a month, it may not simply be a sign of irritation but part of the cellular renewal process. Therefore, it’s essential to pay attention to how the skin reacts and adjust retinoid use as necessary.

For those seeking alternatives, Marta Agustí, nutritional director of the Advanced Nutrition Programme, suggests supplementation with vitamin A, which can be complemented with topical applications to maximize its positive effects.

Among the standout products that incorporate these advancements are Byoode’s Retin-A Night, a serum that stimulates collagen production; Medik8’s Crystal Retinal Ceramide Eye 10, which acts quickly and reduces side effects; and Perricone MD’s Growth Factor Firming & Lifting Serum, which accelerates cellular renewal without causing irritation. Each of these products has been formulated to deliver visible results in skin health and appearance, thus reaffirming their relevance in dermocosmetic care routines.

Source: MiMub in Spanish

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